ISSN 1662-4009 (online)

ey0020.7-1 | Gonadal Function and Fertility Issues in Childhood Cancer Survivors | ESPEYB20

7.1. Childhood cancer and hematological disorders negatively affect spermatogonial quantity at diagnosis: a retrospective study of a male fertility preservation cohort

I Masliukaite , E Ntemou , EAM Feijen , M van de Wetering , A Meissner , AT Soufan , S Repping , LMC Kremer , K Jahnukainen , E Goossens , AMM van Pelt

Brief summary: This multicentre retrospective cohort study evaluated testicular structure in 101 boys aged <14 years with solid tumors, CNS tumors, leukemia/lymphoma, or non-malignant hematological disorders, who were admitted for a fertility preservation programme between 2002 and 2018.The aim of the study was to clarify a possible role of the disease itself on the risk of infertility, independently of cancer therapies. Clinical data, testicular vol...